NEURODESIGN® · CORPUS · updated 2026-08-25
The research corpus
A permanent evidence library for understanding how environments influence the brain, nervous system and behavior. The corpus brings together neuroscience, psychology, physiology, sleep science, sensory research, building science and environmental health, then indexes each source by the mechanism it helps explain and the spatial variable it may inform.
Each record separates two things that are often collapsed. Evidence strength describes how much weight the finding carries within the science itself. Translation distance describes how many inferential steps sit between that finding and a decision about a building. A grid-cell study can be excellent neuroscience and still be several steps away from telling us how to design a corridor.
The library keeps null findings, conflicting results and failed replications alongside positive evidence. It also records what remains unknown. The goal has not been just to collect research that confirms Neurodesign. It is also to build an evidence base strong enough to tell us where design can make a defensible claim, where the science is still developing, and where the most interesting questions have not yet been tested.
- records
- 121
- web-verified
- 121/121
- with DOI
- 99
- direct built environment
- 73
- mechanisms indexed
- 34
- spatial variables
- 42
- anchor reviews
- 25
- known gaps
- 23
The two axes at a glance
Four records, four distances
The same library holds a systematic review of indoor environmental quality, a rodent electrophysiology paper, a sleep-neuroscience mechanism study and an office acoustics experiment. They are not equally close to a design decision, and the corpus says so on every one of them.
ND-0001 · 2021 · Systematic review
How indoor environmental quality affects occupants' cognitive functions: A systematic review
Wang et al. Building and Environment
Poorer indoor conditions were often associated with poorer cognitive performance, but effects varied by factor, task and study design.
ND-0066 · 2006 · Foundational theory/review
The boundary vector cell model of place cell firing and spatial memory
Barry et al. Reviews in the Neurosciences
Proposes that boundaries at specific distances and directions contribute to place-cell firing and spatial memory.
ND-0093 · 2025 · Experimental neuroscience study
Norepinephrine-mediated slow vasomotion drives glymphatic clearance during sleep
Hauglund et al. Cell
Synchronized norepinephrine and vascular oscillations were linked to glymphatic CSF flow during NREM sleep; zolpidem dampened key dynamics.
ND-0022 · 2020 · Experimental study
Irrelevant speech effect in open-plan offices: A laboratory study
Kostallari et al. Applied Acoustics
Irrelevant speech degraded aspects of cognitive task performance in an office-like context.