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ND-0065 · 2010 · Other

HighAdjacent human mechanism

Evidence for grid cells in a human memory network

Doeller, Barry & Burgess. Nature. 2010.

doi.org/10.1038/nature08704 · Web-verified

What the study found

Human entorhinal signals showed six-fold directional modulation consistent with grid-cell-like coding.

Limitations

fMRI is an indirect population-level proxy for single-cell activity; virtual navigation task.

Neurodesign interpretation

This makes the geometry-to-navigation story architecturally relevant, while still leaving a gap between laboratory navigation and real buildings.

Possible design implications

Ground human wayfinding hypotheses in human evidence before extrapolating rodent data.

Why it stays in the corpus

Retain as the canonical human grid-code bridge.

Study design

fMRI experiment

Population

Humans

Setting

Virtual navigation during fMRI

Field

Spatial neuroscience

Mechanism

Grid-like coding in humans

Spatial variable

Virtual navigation geometry

Keywords

human grid cells, entorhinal, fMRI, navigation

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